The use of Hormone Replacement Therapy in menopausal women
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Our population is an aging one, with people living longer and longer every generation. This has led to a disproportionate increase in the incidence of women who suffer from osteoporotic fractures. Bone mass reaches it’s apogee in people in their thirties or forties, and bone loss occurs in most, though not all people from this point on.
Ovarian hormonal secretion and metabolism are well established mechanisms known to be involved in osteoporosis. There are many reasons why these mechanisms have been put forward by physicians these include but are not limited to the following findings:
There is much data that has established that bone loss is much more rapid in women than men;
This bone loss is accelerated in woman upon reaching the menopause;
The skeleton is responsive to hormone replacement therapy;
There is an increase in the number of fractures in women who have a malfunctioning ovarian system.
As mentioned above, the loss of bone typically starts in the third or fourth decade of a woman’s life, it is noteworthy that at this age most women have a perfectly normal hormonal system; this suggests that there must be things other than correct ovarian related endocrine functions involved in osteoporosis. Nonetheless the use of hormone replacement therapy has proved effective in reducing the risks of bone fracture in woman of a certain age.
Author: Deano
Mail: admin@plant-biology.com
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